A genetic factor has been discovered that allows the skin of an adult to regenerate without scars
Researchers have determined that a genetic factor that acts as a molecular switch in the formation of hair follicles in newborns allows adult skin to repair itself like it does in babies.
A team from the University of Washington found that it usually turns off immediately after skin formation in the first weeks of life and remains inactive in tissues for the rest of its life. When, during experiments, scientists activated it in specialized cells in adult mice, the wounds on their skin began to heal without scarring, it had fur and even the goose bumps effect was observed, which is usually absent on scars.
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According to scientists, the open transcription factor Lef1 (proteins that bind to DNA and affect the turning on or off genes) allows you to restore the degenerate ability to regenerate. It is associated with papillary fibroblasts, which develop cells in the papillary dermis, which gives the skin its elasticity and youthful appearance.
In the future, the team will continue to study this factor in order to better understand its mechanism of influence on tissue regeneration, as well as look for other similar switches.
Recall that recently, scientists have developed a new painless way to administer drugs through the skin.
, Washington State University